STAR CLIA Kit for Human(Homo sapiens) | EIAab.comSTAR CLIA Kit for Human(Homo sapiens)

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STAR (Gene name),

Steroidogenic acute regulatory protein, mitochondrial (Protein name ), STAR_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

STAR(STARD1);

Protein name:

Steroidogenic acute regulatory protein, mitochondrial(StAR);

Alternative:

START domain-containing protein 1(StARD1);

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

May interact with TSPO.

Function:

Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone.

Subcellular Location:

Mitochondrion

Protein Attributes:

Sequence length:

285

Sequence:

50:

100:

150:

200:

250:

285:

LPKSIINQVL | SQTQVDFANH | LRKRLESHPA | SEARC

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

MIM:

201710

String:

P49675

Pfam:

PF01852

KEGG:

hsa:6770

SMR:

P49675

UniGene:

Hs.521535

STRING:

9606.ENSP00000276449

Uniprot:

P49675

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ELISA Kit for Human StAR

Cat.:

E15127r

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Packing:

96T

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ELISA Kit for Human StAR

Cat.:

E15127h

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MSDS:

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96T

ELISA Kit for Human StAR

Cat.:

E15127m

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Manual:

Looking for manual.

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Packing:

96T

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ELISA Kit for Human StAR

Cat.:

E15127p

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Packing:

96T

ELISA Kit for Human StAR

Cat.:

E15127b

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96T

ELISA Kit for Human StAR

Cat.:

E15127c

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96T

CLIA Kit for Human StAR

Cat.:

U15127p

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Packing:

96T

CLIA Kit for Human StAR

Cat.:

U15127c

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96T

CLIA Kit for Human StAR

Cat.:

U15127r

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96T

CLIA Kit for Human StAR

Cat.:

U15127b

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Packing:

96T

CLIA Kit for Human StAR

Cat.:

U15127m

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MSDS:

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Packing:

96T

CLIA Kit for Human StAR

Cat.:

U15127h

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Packing:

96T

Polyclonal Antibody for Human StAR

Cat.:

P15127Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human StAR

Cat.:

P15127Rb-h

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human StAR

Cat.:

P15127Rb-r

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Packing:

40ug/0.2ml

Monoclonal Antibody for Human StAR

Protein for Human StAR

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Human steroidogenic acute regulatory protein: functional activity in COS-1 cells, tissue-specific expression, and mapping of the structural gene to 8p11.2 and a pseudogene to chromosome 13."
Sugawara T. , Holt J.A. , Driscoll D. , Strauss J.F. III , Lin D. , Miller W.L. , Patterson D. , Clancy K.P. , Hart I.M. , Clark B.J. , Stocco D.M.
Proc. Natl. Acad. Sci. U.S.A.92:4778-4782(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANT ASP-203
tissue: Adrenal cortex.
2.

"Structure of the human steroidogenic acute regulatory protein (StAR) gene: StAR stimulates mitochondrial cholesterol 27-hydroxylase activity."
Sugawara T. , Lin D. , Holt J.A. , Martin K.O. , Javitt N.B. , Miller W.L. , Strauss J.F. III
Biochemistry34:12506-12512(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANT ASP-203
tissue: Placenta.
3.

"The human steroidogenic acute regulatory (StAR) gene is expressed in the urogenital system and encodes a mitochondrial polypeptide."
Gradi A. , Tang-Wai R. , McBride H.M. , Chu L.L. , Shore G.C. , Pelletier J.
Biochim. Biophys. Acta1258:228-233(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
4.

Yu W. , Sarginson J. , Gibbs R.A.
Submitted (1997-11) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Brain.
5.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Brain.
6.

"The steroidogenic acute regulatory protein (StAR): a window into the complexities of intracellular cholesterol trafficking."
Strauss J.F. III , Kallen C.B. , Christenson L.K. , Watari H. , Devoto L. , Arakane F. , Kiriakidou M. , Sugawara T.
Recent Prog. Horm. Res.54:369-394(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT SER-57 AND SER-195
7.

"Comparative structural analysis of lipid binding START domains."
Thorsell A.G. , Lee W.H. , Persson C. , Siponen M.I. , Nilsson M. , Busam R.D. , Kotenyova T. , Schuler H. , Lehtio L.
PLoS ONE6:E19521-E19521(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (3.40 ANGSTROMS) OF 66-284
8.

"The pathophysiology and genetics of congenital lipoid adrenal hyperplasia."
Bose H.S. , Sugawara T. , Strauss J.F. III , Miller W.L.
N. Engl. J. Med.335:1870-1878(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS AH1 GLY-169; LYS-169; LEU-182; VAL-218; ARG-272 DEL AND PRO-275;CHARACTERIZATION OF VARIANTS
9.

"Analysis of the steroidogenic acute regulatory protein (StAR) gene in Japanese patients with congenital lipoid adrenal hyperplasia."
Nakae J. , Tajima T. , Sugawara T. , Arakane F. , Hanaki K. , Hotsubo T. , Igarashi N. , Igarashi Y. , Ishii T. , Koda N. , Kondo T. , Kohno H. , Nakagawa Y. , Tachibana K. , Takeshima Y. , Tsubouchi K. , Strauss J.F. III , Fujieda K.
Hum. Mol. Genet.6:571-576(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS AH1 VAL-218 AND THR-225
10.

"A novel frameshift mutation 840delA and a novel polymorphism D203A in the steroidogenic acute regulatory protein gene in a Japanese patient with congenital lipoid adrenal hyperplasia."
Katsumata N. , Tanae A. , Shinagawa T. , Nagashima-Miyokawa A. , Shimizu M. , Yasunaga T. , Tanaka T. , Hibi I.
Hum. Mutat. Suppl.1:S304-S307(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT ASP-203
11.

"A novel compound heterozygous mutation in the steroidogenic acute regulatory protein gene in a patient with congenital lipoid adrenal hyperplasia."
Katsumata N. , Kawada Y. , Yamamoto Y. , Noda M. , Nimura A. , Horikawa R. , Tanaka T.
J. Clin. Endocrinol. Metab.84:3983-3987(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS AH1 THR-217 AND VAL-218

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